Innovating Rapid Detection
Monoclonal Antibody &
Lateral Flow Assay Development
Silver Lake Research is driving down the limits of antigen detection worldwide with simple, inexpensive, and accurate rapid testing innovations.
Our EAP™ System has produced thousands of monoclonal antibodies per year for commercial and research use - all for "difficult" or "impossible" targets.
Our rapid diagnostics empower human and veterinary screening programs in some of the most challenging settings worldwide.
Our consumer and environmental test kits are trusted in virtually any environment - from home kitchens, to offshore oil rigs, to nuclear power plants.
Sickle Cell Disease Screening in Newborns
HemoTypeSC is a rapid test for sickle cell disease, featuring unique, EAP-derived MAbs that are highly specific for detection of hemoglobins A, S, and C. HemoTypeSC has been independently validated in dozens of field studies throughout Africa, India, and the Caribbean, repeatedly demonstrating >99% sensitivity and >99% specificity in peer-reviewed publications.
Early, Pen-Side Detection of African Swine Fever
PenCheck is the first validated rapid test for African Swine Fever Virus that is truly on-site – no sample collection, processing, transport, or instrumentation required. This is an antigen-detecting LFA that requires just a drop of blood and delivers results in ~15 minutes. PenCheck demonstrated >95% sensitivity and >99% specificity in multiple validations in the USA and Asia.
Rapid Testing for Bacteriuria in Dogs
RapidBac Vet is a 15-minute test for the detection of Gram-positive and Gram-negative bacteria in the urine of cats and dogs. Results correlate with urine culture, allowing vets to deliver results during the initial office visit, without waiting 2-3 days for culture results. The product has demonstrated >97% sensitivity and specificity in a peer-reviewed publication.
Complete Drinking Water Test Kit:
Lead, Pesticides, Bacteria, & More
The AquaScreen Complete Drinking Water Test Kit contains the most sensitive rapid lead test on the planet, detecting dissolved lead atoms down to 3.8 parts per billion (ppb) - about 5 times more sensitive than the EPA Action Level. With additional lab-validated rapid tests for pesticides, bacteria, nitrates, nitrites, chlorine, hardness, and pH, the AquaScreen test kit is an inexpensive and highly reliable method for ensuring the quality of drinking water - be it well water or municipal water.
The Enhanced Affinity Platform
At Silver Lake Research, we use our powerful Enhanced Affinity Platform to create diverse monoclonal antibody (MAb) panels for detection of traditionally "difficult" or non-immunogenic targets. The EAP™ System was designed to generate a massive immune response to any target antigen - orders of magnitude more potent than standard immunization schemes.
SLR's engineering expertise and vertical integration allow for the cost-effective development and manufacturing of simple, rapid, and highly sensitive lateral flow assay (LFA) test strips. These LFAs bring the power of laboratory testing into the palm of your hand, for confident antigen detection, in the home or out in the field. Importantly, the resulting rapid test kit products are affordable even in resource-constrained regions of the world.
Since 1992, SLR has been a global industry leader in MAb- and LFA-development. Our rapid test products are sold on six continents and are being deployed by governmental organizations and NGOs for public health screening and veterinary disease surveillance. Our outstanding track record of success in contract development projects makes us a trusted resource for the government and private industry partners. We look forward to collaborating with your group to develop the next important rapid test.